Like adding new letters to an existing language’s alphabet to expand its vocabulary, adding new synthetic nucleotides to the genetic alphabet could expand the possibilities of synthetic biology. This ...

“Pursuit of a grand challenge—here, to create artificial life based on different molecular components—forces scientists across uncharted terrain where they must solve unscripted problems,” Steven ...

The genetic alphabet contains just four letters, referring to the four nucleotides, the biochemical building blocks that comprise all DNA. Scientists have long wondered whether it's possible to add ...

Structural comparison of DNA and the artificial TNA, a Xeno nucleic acid with the natural base pairs AT and GC and an additional base pair (XY). The DNA carries the genetic information of all living ...

Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab. The genetic alphabet contains just four ...