Biochemists may soon find themselves reaching for palladium reagents—chemicals once thought to be exclusively used in organic synthesis—to couple small molecules, such as drugs, onto proteins.
The importance of aryl sulfides in biologically active compounds has led chemists to develop methods to synthesize them from carbon-sulfur bond forming reactions. The conventional reaction, however, ...
In recent years, transition-metal-catalyzed carbon-carbon bond-forming chemistries have become essential tools for the development of agrochemical and pharmaceutical active ingredients and other fine ...
In aliphatic or aromatic compounds, the replacement of hydrogen atom(s) by halogen atom(s) results in the formation of alkyl halide (haloalkane) and aryl halide (haloarene), respectively. In case of ...