The cytochrome P450 enzymes form a vast superfamily of haem‐containing monooxygenases that catalyse the metabolism of a broad spectrum of endogenous substances and xenobiotics. Their dynamic catalytic ...
In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists have now derived universal rules to enable the de novo design of optimal enzymes. As an example, they ...
Kanazawa University, have captured real-time images showing how a key brain enzyme organizes itself to help memory formation.
Max Planck Institute for Dynamics and Self-Organization (MPI-DS)May 25 2025 In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists from the Max Planck ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 4 (January 26, 2021), pp. 1-8 (8 pages) We have studied the role of protein dynamics in chemical ...
Abnormal enzyme activity is a hallmark of several diseases including cancer, neurodegeneration, inflammation, and metabolic disorders. Enzyme-activated near-infrared fluorescent probes have emerged as ...
Emory University researchers led by Kyle Biegasiewicz have repurposed enzymes to produce diazo compounds from hydrazones ...
A new model of enzymatic reactions extends the traditional reaction coordinate by considering coupling between the enzyme and the molecule. This way, alternative ways for enzymatic reactions open ...