All bones start off as cartilage. Cartilage generates an abundant and specialized matrix surrounding its cells (extracellular matrix) that promotes the growth of skeletal structures and is pivotal in ...

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

Cartilage injuries are a common clinical issue, often caused by trauma, severe infections, or degenerative joint diseases. The lack of direct blood supply to cartilage and limited access to nutrients ...

Researchers have identified a new mechanism behind knee osteoarthritis, showing that increased stiffening in the extracellular matrix led to a decrease in the Klotho 'longevity protein,' which led to ...

Scientists at Stanford Medicine have discovered a treatment that can reverse cartilage loss in aging joints and even prevent arthritis after knee injuries. By blocking a protein linked to aging, the ...

Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity, and the ...

Effective treatment and repair of damaged cartilage still present a significant challenge for today’s medicine. Researchers at Duke University in the USA have recently created a novel hydrogel-based ...