Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

The conservation of genome regulatory elements over long periods of evolution is not limited to vertebrates, as previously ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...

Plant bioengineering—in which plant genes are modified to include desirable characteristics—is the key to solutions for problems concerning crop resilience and food security. Elements like gene ...

Assessing which genes are active in a given tissue at a specific time, and determining the relative degree of gene activity are essential steps in understanding how the genome as a whole functions ...