Precision BioSciences (DTIL) will present preclinical data supporting the advancement of PBGENE-HBV into clinical development. The company will also outline the design of its first-in-human study, ...
Scientists from Princeton University's Department of Molecular Biology have successfully tested a cell-culture system that will allow researchers to perform laboratory-based studies of long-term ...
The persistence of hepatitis B virus (HBV) covalently closed-circular DNA (cccDNA) and integration of HBV DNA into the hepatocytes lead to chronic HBV infection. Current therapies achieve long-term ...
In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive. Researchers have discovered that cells blood vessels in the liver start a ...
Hepatitis B virus (HBV) infects more than 250 million people worldwide and can lead to chronic liver disease and liver cancer. Current antiviral therapies suppress viral replication but do not ...
Liver infections may not make headlines like the flu or COVID-19, but they quietly impact hundreds of millions of people worldwide. Hepatitis B and C viruses (HBV and HCV) are masters of persistence, ...
HBc inhibits damage-induced mitochondrial fission and selective mitophagy. HBc-triggered Rab7 hyperactivation increases lysosomal fusion while preventing autophagic lysosome reformation. Sustained HBc ...
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Netrin-1 disrupts hepatitis B virus attachment and internalization, offering new treatment path
Hepatitis B virus (HBV) infects more than 250 million people worldwide and can lead to chronic liver disease and liver cancer. Current antiviral therapies suppress viral replication but do not ...
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