AlphaGenome is a leap forward in the ability to study the human blueprint. But the fine workings of our DNA are still largely ...

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- ...

The research team discovered that this type of regulation, which appears to influence the expression of about half of all human genes, is found throughout the animal kingdom, as well as in plants. The ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of ...

Frontotemporal dementia (FTD) often strikes our most human traits, such as the ability to speak and to interact on social and emotional levels. Now, research led by Lorenzo Pasquini and William Seeley ...

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language. Darnell said the switch to the new NOVA1 variant likely occurred between ...