Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an estrogen independent manner. Targeting vimentin and/or the long ...
Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2418624122 Scientists have uncovered new details about cellular filaments that play a critical role in wound healing, ...
We previously demonstrated that truncated desmoplakin I (DP I) molecules containing the carboxyl terminus specifically coalign with and disrupt both keratin and vimentin intermediate filament (IF) ...
This is a preview. Log in through your library . The Journal of Cell Biology (JCB) is a not-for-profit publication, edited by scientists, and a leading life sciences journal. The JCB publishes papers ...
Just as the skeleton and muscles move the human body and hold its shape, the cells of the body are stabilized and moved by a cellular skeleton. This cellular skeleton is a dynamic structure, ...
Just as the human body has a skeleton to give it structure and support, a cell has a cytoskeleton to give it shape and stability. Some of the main structures that make up a cell’s cytoskeleton are ...
Living cells are constantly exposed to a wide variety of mechanical stresses: heart and lungs must withstand expansion and contraction; our skin must be resistant to tearing whilst retaining ...
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