Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...

In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut regeneration and long-term stability. Their findings may have ...

Attrition in the therapeutic pipeline can typically result from a lack of translational efficacy between the pre-clinical phase and the clinic. Organoids offer much promise in drug screening and ...

A team led by Prof. Dr. Dirk Haller has demonstrated for the first time that defective mitochondria cause injuries in the intestinal epithelium and influence the microbiome. In this microscopic image ...

Researchers have developed strategies to identify regulators of intestinal hormone secretion. In response to incoming food, these hormones are secreted by rare hormone producing cells in the gut and ...

What am I looking at? This video shows actin at work in a growing intestinal organoid. The video is depth-coded for color, which means that cooler colors like blue and purple are closer to the viewer ...

The trillions of microbes in our gastrointestinal tract, known as the gut microbiome, are crucial to the body; the gut microbiome aids in digestion, nutrient absorption, and influences our health in ...

People who are infected with chlamydia can transmit these bacteria to other people during unprotected sex. The pathogens usually cause no symptoms, or only mild symptoms at first, such as itching in ...

Molecular Devices UK Ltd offers 3D Ready ™ Organoids in cryopreserved vials, an "off-the-shelf" solution for researchers looking to use physiologically appropriate, patient-derived organoid models ...