Ligand-gated ion channels are ion channels that are opened or closed (gated) by ligands, generally small molecules such as the second messenger cAMP and neurotransmitters. Ligand-gated ion channels ...

Ion channels are transmembrane proteins specifically involved with the transport of inorganic ions like Na+, K+, Ca2+, or Cl-. Ion channels are “gated”, i.e. they open in response to a specific ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 24 (June 16, 2020), pp. 13437-13446 (10 pages) Pentameric ligand-gated ion channels (pLGICs) are ...

Ion channels are membrane proteins, which play a principal role in regulating cellular excitability. They are found in virtually all cells, and are of crucial physiological importance. Based on the ...