Just as a chef perfects a dish by experimenting with flavors and textures, the researchers used an iterative process, testing variations to find the ideal structure for the ionizable lipid. This lipid ...

A by-product of rice bran oil production has long been recognized as a source of beneficial lipids for skin health and nutrition. Now, researchers have uncovered an entirely new class of skin-active ...

Scientists from the University of Pennsylvania have developed an ideal “recipe” for ionizable lipids, which are essential components of lipid nanoparticles (LNPs), the molecules that underlie the ...

New research from scientists at the University of Pennsylvania shows that by tweaking the structure of the ionizable lipid component of lipid nanoparticles (LNPs), they can reduce side effects such as ...

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...

Researchers have identified three previously unknown lipid molecules in rice bran, one of which strengthens the skin's barrier and reduces water loss. Named oryzaceramides A–C, these acylated ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. (Nanowerk News) ...

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids - key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae—responsible for atypical pneumonia and other respiratory infections—to obtain cholesterol ...