The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal ...

MIT scientists have developed a microfluidic chip that mimics the neuromuscular connections that exist at the junction between neurons and the muscles. These junctions are often involved in various ...

The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between muscles and motor neurons, a study concludes. A skeletal muscle isn’t much use without a ...

A research group conducted experiments using aged mice to demonstrate that muscle denervation at the neuromuscular junction (NMJ, *1) could be appreciably offset by an NMJ formation-enhancing ...

Neuromuscular diseases are caused by problems in the way muscle cells, motor neurons, and peripheral cells interact. Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz ...

Though motor neurons are the primary victims in amyotrophic lateral sclerosis, it is their waning connections with muscles that ultimately triggers symptoms of the disease. This complex interaction ...

Neurology encompasses a vast spectrum of disorders that affect the central and peripheral nervous systems, with neuromuscular diseases representing a significant subgroup. These disorders include ...

This week we are going to discuss a topic that we had briefly touched on earlier, the neurologic autoimmune conditions: myasthenia gravis and Lambert Eaton Syndrome (LEMS). To review: Myasthenia ...

Proprioceptive neuromuscular facilitation (PNF) is a form of assisted stretching. It combines passive stretching with muscle contraction. First, your partner applies force to stretch your muscle ...

In a serendipitous discovery, UC San Diego researchers using cryo-EM technology captured the first visualizations of the 3-D structure of the muscle acetylcholine receptor in fetal and adult muscles.