Figure 1: Mechanisms involved in regulation of tumor progression by neutrophil PAD4. “Using several transplantable and genetically engineered mouse models, we demonstrated that tumor growth was ...

Cancer is very difficult to treat due to various components that therapies must address to effectively kill or lyse tumor cells. There are two general categories of cancer: blood or hematologic ...

PMN (Lox-1- PMN) and PMN-MDSC (Lox-1+ PMN) are nearly impossible to distinguish through external features. PMN cells from a patient with head and neck cancer. Scale bars, 20 μm. This material relates ...

Translationally controlled tumor protein (TCTP) is an immunomodulator that initiates development of an inflammatory milieu in the tumor microenvironment, where TCTP regulates high myeloid-derived ...

Durability of complete response (CR) with atezolizumab (atezo) in locally advanced/metastatic urothelial carcinoma (mUC).

Blood myeloid derived suppressor cells (MDSC) in metastatic urothelial carcinoma (mUC) are correlated with neutrophil-to-lymphocyte ratio (NLR) and overall survival (OS). Alterations of DNA damage ...