Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer ...

A study led by researchers at Moffitt Cancer Center found that normal cells surrounding a tumor, known as cancer-associated ...

Chronic circadian disruption — such as night-shift work, irregular schedules, or frequent jet lag — accelerates the ...

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by ...

A new review was published in Oncotarget, Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer." In this review article, Dinara Ryspayeva and colleagues from Brown ...

Disrupted circadian rhythms from night shifts, irregular sleep schedules or frequently flying across time zones can fuel breast cancer risk.

Scientists have uncovered a gut-specific epigenetic aging mechanism that links inflammation and iron imbalance to cancer risk ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

“Using the new method, we can find biological pathways in which genes are significantly mutated or disrupted,” explains Yijun Sun, associate professor of bioinformatics in the Department of ...

As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic ...