The 49ers' win over the Colts had big playoff implications in the AFC. Here are our takeaways from Monday night.

The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will be remembered as the Brock Purdy game. The 49ers quarterback powered San Francisco to a 48-27 road victory with a career-high five passing touchdowns.

The San Francisco 49ers have beaten the Indianapolis Colts 48-27 on “Monday Night Football” behind Brock Purdy’s career-high five touchdown passes. Christian McCaffrey racked up 146 total scrimmage yards and caught two touchdowns,

The Indianapolis Colts host the San Francisco 49ers on "Monday Night Football": Inactives, injury report, who's in, who's out.

The Colts' Monday night loss to the 49ers is the Bills' gain. And the Jaguars'. And the Chargers'. All three teams have officially clinched playoff berths, as a result of the 49ers beating Indianapolis,

Following the Indianapolis Colts' performance on Monday Night Football, here are three takeaways from what took place against the 49ers.

Even with a loss to the 49ers, the Colts can still make the playoffs if they win their remaining games and Houston loses to the Chargers. The Indianapolis Colts have a 3% chance of making the NFL playoffs according to the New York Times Playoff Simulator entering Monday Night Football against the San Francisco 49ers.

San Francisco vs. Indianapolis takes place on Monday Night Football, and bettors can use NFL sportsbook promos at the best NFL betting sites and NFL betting apps