Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...
8don MSN
How major nuclear protein complexes control specialized gene regulation in cancer and beyond
Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...
A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled “A ...
Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...
DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...
UCSF scientists engineered old fibroblast cells to turn their genes on and off in the same way as young fibroblasts. The old ...
News-Medical.Net on MSN
RNA splicing and processing genes emerge as central drivers of aging across tissues
A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A ...
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