Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression. These are some of ...

Researchers have made a significant step towards enabling women with epilepsy safer access to a common and highly effective anti-seizure medication. Sodium Valproate or valproic acid is widely ...

Feb. 6, 2004 — Valproic acid has no effect on pain in polyneuropathy, according to the results of a randomized, double-blind, placebo-controlled study published in the Jan. 27 issue of Neurology.

Over ten years ago, the Food and Drug Administration (FDA) determined that pregnant women who take Depakote (valproate) have a much higher chance of giving birth to a baby who suffers low IQ or a ...

Valproic acid (VPA), formally 2-propylpentanoic acid, is a low–molecular weight branched-chain fatty acid. It is a derivative of valeric (pentanoic) acid1, which occurs naturally in valerian ...

SAINT-DENIS, France — France's national agency for health and product safety, L'Agence nationale de sécurité du médicament et des produits de santé (ANSM), and the national insurance fund for employed ...

Presurgical evaluation of the AKT inhibitor MK-2206 in patients with operable invasive breast cancer. Background: Valproic acid (VPA) is a histone deacetylase (HDAC) inhibitor that increases apoptosis ...

Paternal use of the anti-seizure medication valproate during spermatogenesis was not associated with a risk of congenital malformations or neurodevelopmental disorders in offspring, an observational ...

The introduction of a stricter approval process for prescribing an anti-seizure drug that can cause birth defects when taken during pregnancy has been effective at reducing the number of prescriptions ...