Nipah virus and Hendra virus are bat-borne zoonotic pathogens responsible for outbreaks of encephalitis and respiratory illness. Notably, these henipaviruses have fatality rates between 50% and 100%.
Recent molecular findings offer new details on how Nipah and Hendra viruses attack cells, and the immune responses that try to counter this onslaught. The results point toward multi-pronged tactics to ...
Hepatitis B virus (HBV) infects more than 250 million people worldwide and can lead to chronic liver disease and liver cancer. Current antiviral therapies suppress viral replication but do not ...
In a recent study published in the journal Nature, researchers use cryogenic electron microscopy (cryo-EM) in tandem with molecular dynamics simulation to reveal that the usually closed spike proteins ...
One of the defining features of viruses is that they rely on host proteins in order to reproduce. A host cell will often copy viral genes into RNAs and then translate those RNAs into proteins, for ...
The ongoing coronavirus disease 2019 (COVID-19) pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This is a highly infectious RNA virus belonging to the family ...
Researchers recently discovered that a virus, FloV-SA2, encodes one of the proteins needed to make ribosomes, the central engines in all cells that translate genetic information into proteins, the ...
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Key human proteins that power coronavirus replication point to new treatment strategies
Despite vaccines and treatments, SARS-CoV-2—the virus that causes COVID-19—continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still ...
3D structural findings are reported on a critical component of the Nipah virus' infection mechanism, and how antibodies home in on an important part of the machinery that attaches the virus to host ...
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