The mechanistic significance of centrosome aberrations for the induction of chromosomal instability has been a matter of intensive debate as well. On the one hand, it has been proposed that abnormal ...
Centrosomes, which are composed of two centrioles and pericentriolar material, serve as the main microtubule-organizing centre in animal cells. They duplicate once per cell cycle so that each daughter ...
In a new study, Dana-Farber Cancer Institute scientists disprove a century-old theory about why cancer cells often have too many or too few chromosomes, and show that the actual reason may hold the ...
The centrosome is the organelle responsible for the organization of the cytoskeleton during cell division, an essential function in organisms from yeast to humans. Until now, scientists assumed that ...
Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled. The study focuses on neuronal growth ...
The origin of the centrosome has been controversial for many years. The theory of symbiogenesis as a mechanism of evolution has also stirred debate since it was introduced in the 1920s and ...
Intra-patient genomic heterogeneity of single circulating tumor cells (CTCs) associated to phenotypic CTC heterogeneity in metastatic castrate resistant prostate cancer (mCRPC). SOD2 rs4880 CT/CC ...
When cells extend, move, or divide, a tiny organelle called the centrosome provides a cytoskeletal anchor and regulatory hub. It was long held that centrosomes are similar in composition across cells.
Non Adherence to Post Surgery Annual Surveilance Mammogram and Follow Up Among Breast Cancer Survivors in a Tertiary Care Hospital in Malaysia Modern chemotherapeutics frequently suffer from selective ...
Unseen and ongoing, thousands of times every second: to keep a complex organism like humans alive, an immense number of new cells must be continuously produced. Up close, each of these cell divisions ...
Cytotoxic drugs or cytostatics are drugs used to destroy cancer cells. Cytotoxic drugs inhibit cell division and in this way cause cancer cells to die. But current treatments inevitably have negative ...
The centrosome is the organelle responsible for the organization of the cytoskeleton during cell division, an essential function in organisms from yeast to humans. Until now, scientists assumed that ...
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