San Francisco 49ers head coach Kyle Shanahan said after Monday's win over the Indianapolis Colts that quarterback Brock Purdy ...

San Francisco 49ers head coach Kyle Shanahan talks to the media after Week 16 win against the Indianapolis Colts about goals ...

Watch the best plays from San Francisco 49ers tight end George Kittle's 115-yard game vs. the Indianapolis Colts in Week 16 ...

Watch the best plays from San Francisco 49ers quarterback Brock Purdy's 5-touchdown game vs. the Indianapolis Colts in Week ...

Watch the best plays from Indianapolis Colts quarterback Philip Rivers' 277-yard, two-touchdown game against the San ...

Watch the top touchdowns from Week 16 of the 2025 NFL season. Highlights from the Week 16 matchup between the San Francisco ...

Watch the best plays from San Francisco 49ers running back Christian McCaffery's 146-yard game against the Indianapolis Colts ...

Watch the best plays by the San Francisco 49ers against the Indianapolis Colts in Week 16 of the 2025 NFL season.

Indianapolis Colts quarterback Philip Rivers throws a deep 33-yard pass to wide receiver Alec Pierce. Indianapolis Colts ...

Watch the top defensive plays from Week 16 of the 2025 NFL season. Highlights from the Week 16 matchup between the San ...

Watch the top plays from Week 16 of the 2025 NFL season. Indianapolis Colts cornerback Camryn Bynum takes advantage of the ...

Watch the top runs from Week 16 of the 2025 NFL season. Indianapolis Colts cornerback Camryn Bynum takes advantage of the ...