This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

There are any number of random, oddball bets offered on the prediction market Polymarket, though few are quite as curious as ...

A variation of a puzzle called the “pick-up sticks problem” asks the following question: If I have some number of sticks with random lengths between 0 and 1, what are the chances that no three of ...

Complex organizational problems and chaos are silent killers of productivity and innovation. In today’s fractured work environment, they are more prevalent than ever. Political transitions, ...

If you want to accentuate the importance of a problem, it seems sensible to explain how prevalent it is. Lots of people are at risk of Alzheimer’s disease. Lots of women carry a gene that makes them ...

Life is uncertain. None of us know what is going to happen. We know little of what has happened in the past or is happening now outside our immediate experience. Uncertainty has been called the ...

On Dec. 22, 1999, Warner Bros. released the Oliver Stone-directed NFL drama in theaters. By Kirk Honeycutt On Dec. 22, 1999, Warner Bros. released the Oliver Stone-directed NFL drama Any Given Sunday ...

Current AI models struggle to solve research-level math problems, with the most advanced AI systems we have today solving just 2% of the hundreds of challenges faced. When you purchase through links ...

The mathematician Daniel Litt has driven social media users to distraction with a series of simple-seeming but counterintuitive probability puzzles. In late January, Daniel Litt posed an innocent ...

For the past month or so, you could hardly log onto any social media platform without hearing Laila!‘s TikTok-viral single “That’s Not My Problem.” The song became so popular online, that Cash Cobain ...

AlphaProof and AlphaGeometry 2 are steps toward building systems that can reason, which could unlock exciting new capabilities. AI models can easily generate essays and other types of text. However, ...